Health Signal Africa

Public health intelligence

Reporting windows, geographic coverage and the limits of a signal.

Read dated developments and population-health research with their original scope intact. This desk publishes source-based reporting and attributed evidence briefings. It does not display a live disease forecasting model or treat historical study counts as current surveillance.

Public health, in context

A health worker screens a young child for acute malnutrition at a community nutrition outreach site in Somalia. Expanding early screening, therapeutic feeding and access to essential healthcare is critical to protecting vulnerable children amid worsening food insecurity.
Public Health

Somalia’s Child Malnutrition Crisis Deepens as Flood Risks and Aid Cuts Threaten Lives

Standfirst: Nearly 1.92 million children aged 6–59 months in Somalia are projected to experience acute malnutrition between July 2026 and June 2027. With severe food insecurity, anticipated flooding and shrinking humanitarian support threatening access to essential services, urgent action is needed to protect vulnerable children.

Clinical course of SUDV-infected IFNAR-/- mice.The experimental approach is shown in (A). Female (F) and male (M) IFNAR-/- mice were infected with approx. 1,000 PFU SUDV on day 0 (n = 6) and monitored daily. The mice were euthanized at humane clinical endpoint (score of ≥10 on one day or ≥6 on two consecutive days). Blood samples were collected at day 3, and on the day of euthanasia. The additive clinical score (B), summarizes the results of the different parameters analyzed daily: (C) body weight, behaviour, and appearance. Each parameter could be awarded a maximum of 10 points. Grey boxes indicate days after euthanasia. The relative body weight compared to day 0 for each mouse is depicted in (D). The dotted line marks the clinical endpoint. The Kaplan-Meier survival curve (E) depicts the percentage of surviving mice over time.
Public Health

Sudan virus inflammation in IFNAR-deficient mice

From the abstract: “C57BL/6J IFNAR-/- mice, which lack the type I interferon (IFN-α/β) receptor, have been reported to be susceptible to filovirus infections, although their impaired innate immune response may represent a potential limitation of the model.”

Editorial illustration: Adolescent sleep health in Africa: a research review
Public Health

Adolescent sleep health in Africa: a research review

From the abstract: “This review aimed to map the studies on adolescent sleep health in Africa with a focus on the geographical distribution, publication trends, pattern of sleep health measures, prevalence of sleep disorders, the barriers and facilitators to good sleep health, rural-urban disparities, as well as the associations of sleep health with mental health, school schedule and cardio-metabolic risk among the adolescents.”

Associations between body composition and LAZ at 2 years of age.Data are shown for a total of 223 CHEU and CHU combined. Black square = CHEU, hollow circle = CHU. Line of best fit is from a linear regression model with shading representing the 95% confidence interval. A) Total skinfold thickness. B) Lean mass index. C) Knee-heel length. D) MUAC Z-score.
Public Health

Body composition of HIV-exposed, uninfected children in rural Zimbabwe

From the abstract: “In a substudy among 223 children (36 CHEU and 187 CHU) enrolled in the Sanitation Hygiene Infant Nutrition Efficacy (SHINE) trial in rural Zimbabwe, we measured height, knee-heel length, weight, calf circumference, skinfold thicknesses (triceps, subscapular and calf), and bio-electrical impedance at 2 years of age.”